The effect of hypertension comorbidity in type 2 diabetes on inflammation, cardiovascular risk and hepatorenal function.
Loading...
Date
2021-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Namibia University of Science and Technology
Abstract
The prevalence of non‐communicable diseases such as type 2 diabetes mellitus (T2D) has rapidly
increased over the years and has exerted a major burden on health systems worldwide. T2D is one of
the top ten leading causes of global mortality driven by various T2D‐related complications such as
cardiovascular disease (CVD) and altered hepatorenal function. Notably, hypertension (HTN) is the
most common comorbidity in T2D, with both being independent risk factors for CVD. Although the
underlying pathophysiological mechanisms for this bi‐directional relationship are multifactorial,
chronic inflammation is implicated in the progression of T2D and the pathogenesis of its associated
complications. Since HTN is at least in part, an immune‐mediated inflammatory disorder, this study
aimed at investigating its compounding effects in T2D on inflammation, cardiovascular risk and
hepatorenal function.
Description
Keywords
Hypertension, Diabetes, Cardiovascular disease
Citation
Groenewald, E. J. (2021). The effect of hypertension comorbidity in type 2 diabetes on inflammation, cardiovascular risk and hepatorenal function. (Unpublished master's thesis). Namibia University of Science and Technology, Windhoek.